As Level 2+ autonomous vehicles reach 10% of the US fleet by 2030 and 65% by 2040, buildings delivered today with 30-year holds will spend most of their useful life in a transportation regime different from the one for which they were designed. Community improvement districts will have to decide whether to plan the transition deliberately or be forced to retrofit and tear down expensive buildings later at a higher cost. The challenge for real estate companies will be to uncover underpriced assets in overlooked locations most transformed by autonomous central highways and expanded central business districts.